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What disease is caused by trisomy 21?

Asperger syndrome

cri-du-chat (cat meowing syndrome)

Down syndrome

Patau syndrome

Most cases of Down syndrome are caused by trisomy 21. Occasionally, the extra chromosome #21 or a portion of it is attached to another chromosome in the egg or sperm; this may cause "translocation Down syndrome." This is the only form of Down syndrome that may be inherited from a parent.

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100%

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11

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3%

90%

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33

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7%

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88%

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142

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2%

86%

2%

36

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5%

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20

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11%

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80%

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10296

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79%

12%

24

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14%

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78%

7%

14

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23%

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76%

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17

the United States

12%

6%

75%

2%

141

the United Kingdom

14%

2%

75%

5%

137

Austria

6%

12%

75%

6%

16

Italy

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75%

16%

12

Denmark

10%

10%

70%

10%

10

Republic of Ireland

5%

5%

69%

15%

39

India

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12%

66%

5%

166

France

13%

20%

66%

0%

15

the Philippines

19%

14%

57%

0%

21

Nigeria

28%

20%

48%

4%

25

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