10 most difficult diseases riddles

The Plagues of Egypt were ten calamities that, according to the biblical Book of Exodus, God inflicted upon Egypt as a demonstration of power, after which the Pharaoh conceded to Moses' demands to let the enslaved Israelites go into the wilderness to make sacrifices. God repeatedly hardened the Pharaoh's heart to prevent him from consenting until after the tenth plague. The Israelites' eventual departure began the Exodus of the Hebrew people.

Scrapie is infectious and incurable. Recent studies suggest prions may be spread through urine and persist in the environment for decades. Scrapie occurs in Europe and North America, but to date, Australia and New Zealand (both major sheep-producing countries) are scrapie-free.

Melasma is a tan or dark skin discoloration. Melasma is thought to be caused by sun exposure, genetic predisposition, hormone changes, and skin irritation. Although it can affect anyone, melasma is particularly common in women, especially pregnant women and those who are taking oral or patch contraceptives or hormone replacement therapy (HRT) medication

Disulfiram (sold under the trade names Antabuse and Antabus) is a drug used to support the treatment of chronic alcoholism by producing an acute sensitivity to ethanol (drinking alcohol).

Colloquial names of syphilis in European countries reflected the path of its spread through the continent. In Italy it was named French disease. In France it used to be called Italian or English disease, in the Netherlands a Spanish disease, German one in Poland and Lithuania, and Polish in Russian Muscovy. It never got named American one, despite the dominant hypothesis of its origin.

Zika virus (ZIKV) is spread by daytime-active Aedes mosquitoes. Its name comes from the Ziika Forest of Uganda, where the virus was first isolated in 1947. Zika virus is related to the dengue, yellow fever, Japanese encephalitis, and West Nile viruses. From 2007 to 2016, the virus spread eastward, across the Pacific Ocean to the Americas, leading to the 2015–16 Zika virus epidemic.

Cushing's syndrome is caused by either excessive cortisol-like medication such as prednisone or a tumor that either produces or results in the production of excessive cortisol by the adrenal glands. About two to three people per million are affected each year. It most commonly affects people who are 20 to 50 years of age.Women are affected three times more often than men.

Australia was the first country in the world to introduce plain packaging, with all packets sold from 1 December 2012 being sold in logo-free, drab dark brown packaging. There has been opposition from tobacco companies to plain packaging laws, some of which have sued the Australian government. Since the Australian government won the court cases, several other countries have enacted plain packaging laws.

In a 2011 interview with Harry Potter creator J.K. Rowling, Daniel Radcliffe (the actor that portrayed Harry) revealed that there had been several pairs of the iconic round-rimmed Harry Potter glasses in the beginning of filming as they’d discovered he was allergic to the plastic used in the original pair.

Tuberculosis, also known as "the white plague", had a high mortality rate before streptomycin was introduced as a treatment in 1943. There may have been as many as 64,000 deaths at Waverly Sanatorium in Kentucky. During the TB years, tunnel was also used to transport the dead, so they wouldn't be seen by other patients. The tunnel is supposed to be haunted by those who made their last journey through it.