Mars colonisation is a hype topic. What is the biggest threat for those wishing to take a part in a journey to Mars?

low temperatures
lack of oxygen
poor gravity
cosmic rays
The only efficient protection against high energetic cosmic radiation, one we are granted with, is Earth's magnetic field. Both during a long flight to Mars and through the stay on the planet, that did not form electromagnetic field, astronauts would be exposed to ionization.
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Very interesting!
reach: rather globalastronauticsastronomyMarsphysicsplanetsSolar Systemtechnology

Answers by country

low temperatures
lack of oxygen
poor gravity
cosmic rays
answers
flagthe Netherlands
6%
10%
6%
75%
48
flagAustralia
5%
19%
6%
67%
100
flagFrance
7%
21%
10%
60%
38
flagGreece
6%
21%
6%
59%
32
flagRepublic of Ireland
6%
31%
3%
59%
32
flagAustria
6%
28%
5%
57%
163
flagGermany
9%
26%
6%
55%
1178
flagUnknown
11%
23%
11%
53%
52
flagSwitzerland
14%
23%
9%
49%
122
flagCanada
8%
30%
8%
49%
69
flagPoland
10%
30%
8%
48%
20124
flagthe United States
8%
32%
8%
48%
577
flagthe United Kingdom
9%
33%
9%
47%
287
flagPakistan
11%
32%
11%
43%
53
flagthe United Arab Emirates
14%
28%
14%
39%
28
flagMalaysia
12%
33%
12%
37%
24
flagIndia
10%
37%
13%
36%
1064
flagthe Philippines
10%
47%
9%
32%
106
flagNigeria
8%
52%
8%
32%
25
flagGhana
0%
53%
19%
23%
26