Mars colonisation is a hype topic. What is the biggest threat for those wishing to take a part in a journey to Mars?

low temperatures
lack of oxygen
poor gravity
cosmic rays
The only efficient protection against high energetic cosmic radiation, one we are granted with, is Earth's magnetic field. Both during a long flight to Mars and through the stay on the planet, that did not form electromagnetic field, astronauts would be exposed to ionization.
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Very interesting!
reach: rather globalastronauticsastronomyMarsphysicsplanetsSolar Systemtechnology

Answers by country

low temperatures
lack of oxygen
poor gravity
cosmic rays
answers
flagthe Netherlands
5%
10%
5%
76%
38
flagAustralia
3%
18%
4%
70%
82
flagSpain
0%
29%
5%
64%
17
flagGreece
7%
22%
3%
59%
27
flagGermany
11%
22%
6%
57%
432
flagFrance
7%
25%
10%
57%
28
flagRepublic of Ireland
10%
31%
0%
57%
19
flagAustria
7%
24%
7%
56%
65
flagUnknown
11%
23%
11%
53%
52
flagSwitzerland
7%
23%
10%
51%
39
flagPoland
10%
31%
8%
48%
18194
flagthe United Kingdom
8%
33%
9%
48%
210
flagthe United States
8%
32%
8%
47%
417
flagCanada
9%
30%
9%
47%
53
flagPakistan
8%
31%
11%
45%
35
flagSingapore
0%
40%
20%
40%
15
flagIndia
9%
36%
13%
38%
812
flagthe United Arab Emirates
13%
30%
17%
34%
23
flagthe Philippines
9%
45%
10%
33%
93
flagMalaysia
18%
25%
18%
31%
16