Mars colonisation is a hype topic. What is the biggest threat for those wishing to take a part in a journey to Mars?

low temperatures
lack of oxygen
poor gravity
cosmic rays
The only efficient protection against high energetic cosmic radiation, one we are granted with, is Earth's magnetic field. Both during a long flight to Mars and through the stay on the planet, that did not form electromagnetic field, astronauts would be exposed to ionization.
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Very interesting!
reach: rather globalastronauticsastronomyMarsphysicsplanetsSolar Systemtechnology

Answers by country

low temperatures
lack of oxygen
poor gravity
cosmic rays
answers
flagthe Netherlands
5%
11%
5%
73%
34
flagAustralia
3%
18%
4%
71%
81
flagSpain
0%
31%
6%
62%
16
flagGreece
7%
23%
3%
61%
26
flagGermany
11%
21%
6%
59%
383
flagAustria
6%
25%
6%
58%
60
flagRepublic of Ireland
10%
31%
0%
57%
19
flagFrance
4%
28%
12%
56%
25
flagUnknown
11%
23%
11%
53%
52
flagIndonesia
20%
26%
0%
53%
15
flagSwitzerland
7%
21%
10%
52%
38
flagCanada
9%
31%
5%
49%
51
flagthe United Kingdom
8%
32%
9%
48%
205
flagPoland
11%
31%
8%
47%
17949
flagthe United States
8%
33%
8%
47%
403
flagPakistan
8%
29%
11%
47%
34
flagSingapore
0%
40%
20%
40%
15
flagIndia
9%
37%
13%
37%
761
flagthe United Arab Emirates
13%
31%
13%
36%
22
flagthe Philippines
10%
44%
11%
32%
86