Which infectious agent causes diseases that are the most difficult to cure?

bacteria
virus
fungus
prion
All known prion diseases affect the structure of the brain or other neural tissue and all are currently untreatable and universally fatal. This includes bovine spongiform encephalopathy (BSE, also known as "mad cow disease") in cattle and Creutzfeldt–Jakob disease (CJD) in humans.
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Answers by country

bacteria
virus
fungus
prion
answers
flagItaly
3%
20%
0%
75%
29
flagPakistan
5%
23%
6%
63%
125
flagMalaysia
0%
32%
5%
62%
37
flagGreece
6%
30%
3%
60%
33
flagGermany
7%
30%
4%
56%
267
flagPoland
8%
28%
7%
54%
22073
flagAustralia
13%
27%
5%
52%
73
flagGhana
4%
45%
0%
50%
24
flagIndia
4%
39%
6%
48%
781
flagthe Netherlands
6%
29%
12%
48%
31
flagRepublic of Ireland
16%
30%
2%
47%
36
flagthe United Kingdom
5%
39%
7%
46%
301
flagthe United States
7%
38%
6%
45%
959
flagCanada
6%
43%
4%
45%
81
flagSwitzerland
4%
44%
8%
44%
50
flagIndonesia
15%
35%
10%
40%
20
flagNigeria
3%
57%
0%
39%
33
flagthe United Arab Emirates
13%
27%
13%
37%
29
flagAustria
14%
46%
4%
36%
50
flagthe Philippines
14%
44%
5%
33%
103