Which infectious agent causes diseases that are the most difficult to cure?

bacteria
virus
fungus
prion
All known prion diseases affect the structure of the brain or other neural tissue and all are currently untreatable and universally fatal. This includes bovine spongiform encephalopathy (BSE, also known as "mad cow disease") in cattle and Creutzfeldt–Jakob disease (CJD) in humans.
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Answers by country

bacteria
virus
fungus
prion
answers
flagItaly
5%
26%
0%
67%
34
flagPakistan
6%
23%
6%
62%
133
flagMalaysia
2%
33%
6%
58%
48
flagGreece
5%
33%
2%
58%
36
flagPoland
8%
28%
7%
55%
23733
flagAustralia
11%
27%
4%
55%
94
flagRepublic of Ireland
10%
29%
3%
55%
65
flagthe Netherlands
6%
28%
8%
53%
45
flagCanada
6%
36%
5%
50%
106
flagGermany
7%
36%
5%
49%
712
flagGhana
3%
48%
0%
48%
27
flagIndia
4%
42%
6%
45%
950
flagthe United States
7%
39%
6%
44%
1066
flagthe United Kingdom
5%
42%
6%
43%
406
flagAustria
10%
41%
3%
43%
121
flagSwitzerland
4%
43%
8%
43%
85
flagNigeria
1%
55%
1%
42%
69
flagSouth Africa
7%
38%
7%
42%
26
flagthe United Arab Emirates
11%
34%
11%
37%
35
flagthe Philippines
13%
48%
5%
32%
114