Which infectious agent causes diseases that are the most difficult to cure?

bacteria
virus
fungus
prion
All known prion diseases affect the structure of the brain or other neural tissue and all are currently untreatable and universally fatal. This includes bovine spongiform encephalopathy (BSE, also known as "mad cow disease") in cattle and Creutzfeldt–Jakob disease (CJD) in humans.
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Answers by country

bacteria
virus
fungus
prion
answers
flagItaly
10%
26%
0%
63%
38
flagPakistan
6%
23%
6%
62%
143
flagGreece
5%
31%
2%
60%
38
flagMalaysia
2%
34%
6%
58%
50
flagRepublic of Ireland
10%
27%
2%
57%
69
flagPoland
8%
28%
7%
55%
24421
flagAustralia
11%
28%
6%
54%
100
flagthe Netherlands
8%
28%
8%
52%
46
flagCanada
7%
36%
6%
50%
113
flagGermany
7%
37%
6%
47%
939
flagthe United States
7%
38%
6%
45%
1108
flagAustria
9%
39%
4%
45%
166
flagSwitzerland
6%
41%
6%
45%
107
flagIndia
4%
41%
7%
44%
998
flagthe United Kingdom
5%
42%
6%
44%
433
flagNigeria
1%
51%
2%
43%
80
flagGhana
3%
46%
3%
43%
32
flagthe United Arab Emirates
13%
32%
10%
37%
37
flagSouth Africa
13%
34%
10%
37%
29
flagthe Philippines
13%
48%
5%
31%
121