Which infectious agent causes diseases that are the most difficult to cure?

bacteria
virus
fungus
prion
All known prion diseases affect the structure of the brain or other neural tissue and all are currently untreatable and universally fatal. This includes bovine spongiform encephalopathy (BSE, also known as "mad cow disease") in cattle and Creutzfeldt–Jakob disease (CJD) in humans.
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Answers by country

bacteria
virus
fungus
prion
answers
flagItaly
3%
22%
0%
74%
31
flagPakistan
5%
23%
6%
63%
128
flagMalaysia
0%
31%
6%
61%
44
flagGreece
5%
32%
2%
58%
34
flagGermany
7%
32%
3%
56%
340
flagPoland
8%
28%
7%
54%
22547
flagAustralia
12%
29%
4%
52%
82
flagthe Netherlands
5%
29%
11%
50%
34
flagRepublic of Ireland
13%
32%
2%
48%
43
flagGhana
4%
48%
0%
48%
25
flagIndia
4%
40%
6%
47%
838
flagSouth Africa
8%
30%
8%
47%
23
flagCanada
6%
43%
4%
45%
81
flagSwitzerland
3%
43%
7%
45%
53
flagthe United States
7%
39%
6%
44%
1005
flagthe United Kingdom
5%
41%
7%
44%
351
flagNigeria
1%
57%
1%
38%
52
flagAustria
13%
44%
3%
37%
59
flagthe United Arab Emirates
13%
30%
13%
36%
30
flagthe Philippines
14%
46%
5%
32%
107