Which major South American city remained completely isolated by road for most of its history until the construction of a bridge in the mid-20th century?

Cali
Manaus
Curitiba
Maracaibo
Until the construction of the General Rafael Urdaneta Bridge in the 1950's and 60's, Maracaibo's only connection to the rest of the country was by boat across Lake Maracaibo
Liam
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Very interesting!
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